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Writer's pictureMadhuvanthi Mohan

Loss of pattern!

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ā£Specific conditions:ā£ ā£ Age relatedā£ ā— Atrophy of both iris stroma and pigment epithelial layer occurs as a natural aging processā£ ā— Bilateral, symmetric iris stromal atrophy.ā£ ā— Normal pupillary contour with increased prominence of the pigment epithelium andā£ the pupillary sphincter- tan ringsā£ ā£ Viral Uveitisā£ ā— Chronic inflammation can lead to characteristic iris stromal atrophyā£ ā— VZV generally produces sector iris atrophy due to a vascularā£ occlusive vasculitis, whereas HSV usually produces patchy iris atrophyā£ ā£ Essential iris atrophyā£ ā— ICE syndrome, unilateralā£ ā— Primary defect is believed to be a cellular membrane secreted by the abnormal endothelial cells which covers the iris and the drainage angle of the eye- contraction leads to pupillary changes and formation of PAS - angle closure glaucomaā£ ā— Displaced or distorted pupil, patchy areas of iris atrophy and holes in iris.ā£ ā£ Traumaā£ Post cataract surgery due to trauma to iris can lead to iris atrophy after many years.ā£ ā£ Pigment Dispersion Syndromeā£ ā— Pigment granules settle on iris surfaceā£ ā— Posterior bowing of mid peripheral irisā£ ā— Classic mid peripheral,radial slit like transillumination defects in iris bestā£ seen on retroillumination.ā£ ā£ PXF syndromeā£ ā— Particulate pigment deposition on sphincter and peripheral irisā£ ā— Moth-eaten transillumination defects occur at the sphincterā£ ā£ Post acute congestive glaucomaā£ ā— Partial/total absence of pupillary ruffā£ ā— Sphincter atrophyā£ ā— Whorling of the iris radial patternā£ ā— Sectoral iris atrophyā£ ā£ Fuchā€™s Uveitisā£ ā— Diffuse atrophy of stroma and posterior pigment epithelium of iris.ā£ ā— Determines the quality of heterochromia iridis.ā£ ā£ Albinismā£ ā— Tyrosinase-negative: Lack of melaninā£ ā— Iris is diaphanous and translucent giving rise to a ā€˜pink-eyed appearanceā€™ā£ ā— Tyrosinase-positive: synthesise variable amounts of melanin.ā£ ā— Iris may be blue or dark-brown, variable translucencyā£ ā£ Axenfeld Rieger Syndromeā£ ā— Iris strands adherent to the posterior embryotoxon can range from fine threadlike strands to broad bands of iris tissue.ā£ ā— Stroma - generalized atrophy with corectopia, ectropion uveae

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